Theory and practice of using solvent paramagnetic relaxation enhancement to characterize protein conformational dynamics.


Paramagnetic relaxation enhancement (PRE) has been established as a powerful tool in NMR for investigating protein structure and dynamics. The PRE is usually measured with a paramagnetic probe covalently attached at a specific site of an otherwise diamagnetic protein. The present work provides the numerical formulation for probing protein structure and… (More)
DOI: 10.1016/j.ymeth.2018.04.006


  • Presentations referencing similar topics