Theory and Algorithms for the Haplotype Assembly Problem∗

@inproceedings{Schwartz2009TheoryAA,
  title={Theory and Algorithms for the Haplotype Assembly Problem∗},
  author={Russell Schwartz},
  year={2009}
}
Genome sequencing studies to date have generally sought to assemble consensus genomes by merging sequence contributions from multiple homologous copies of each chromosome. With growing interest in genetic variations, however, there is a need for methods to separate these distinct contributions and assess how individual homologous chromosome copies differ from one another. An approach to this problem was developed using small sequence fragments derived from shotgun sequencing studies to… CONTINUE READING
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A dynamic programming algorithm for the k-haplotyping problem

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