Theories of the Pathogenesis of Inclusion Body Myositis

@article{Greenberg2010TheoriesOT,
  title={Theories of the Pathogenesis of Inclusion Body Myositis},
  author={Steven A. Greenberg},
  journal={Current Rheumatology Reports},
  year={2010},
  volume={12},
  pages={221-228}
}
  • S. Greenberg
  • Published 16 April 2010
  • Biology, Medicine
  • Current Rheumatology Reports
Inclusion body myositis is a progressive disease of the skeletal muscle. Here, specific theories of its pathogenesis are reviewed and general considerations pertaining to modeling of this disease discussed. Understanding of inclusion body myositis disease mechanism remains extremely poor. Current published animal models do not represent the disease. Future studies need to consider the critical role of biomarkers and methodologic issues in their discovery. 
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