Theoretical studies of the quinolinic acid to nicotinic acid mononucleotide transformation.

Abstract

Quinolinate phosphoribosyl transferase (QPRTase) is an essential enzyme that catalyzes the transformation of quinolinic acid (QA) to nicotinic acid mononucleotide (NAMN), a key step on the de novo pathway for nicotinamide adenine dinucleotide (NAD) biosynthesis. We describe herein a theoretical study of the intrinsic energetics associated with the possible… (More)
DOI: 10.1021/jo8012379

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@article{Rozenberg2008TheoreticalSO, title={Theoretical studies of the quinolinic acid to nicotinic acid mononucleotide transformation.}, author={Aleksandr Rozenberg and Jeehiun K Lee}, journal={The Journal of organic chemistry}, year={2008}, volume={73 23}, pages={9314-9} }