Theoretical model of external spinal cord stimulation

  title={Theoretical model of external spinal cord stimulation},
  author={Mikhail N. Shneider and Mikhail Pekker},
  journal={Physical Biology},
In this paper, a simple theoretical model of the excitation of action potentials of multiple motor pools by stimulating current pulses over the lumbosacral regions of the spinal cord is presented. The present model is consistent with known experimental data. 
2 Citations

The possibility of anesthesia stimulated by a train of current pulses

The proposed model allows the selection of parameters and the required frequency of the repetition of current pulses for the possible implementation of anesthesia depending on the electrical characteristics of the skin and the conductivity of the saline solution in which the myelinated nerve fibers are located.

Physical model of electrical synapses in a neural network

A theoretical model of electrical synapses is proposed, in which connexons play the role of “nails” that hold unmyelinated areas of neurons at a distance of about 3.5 nm, and the electrical



Recruitment of dorsal column fibers in spinal cord stimulation: influence of collateral branching

It was found that transmembrane potentials, due to external monopolar stimulation, at the node at which a collateral is attached, is significantly influenced by the presence of the collateral.

Correlation of action potentials in adjacent neurons

A possible mechanism for the synchronization of action potential propagation along a bundle of neurons (ephaptic coupling) is considered. It is shown that this mechanism is similar to the salutatory

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A computational model and in vivo experiments were designed and performed to investigate the type of fibers, neurons, and circuits recruited in response to EES to provide a mechanistic framework for the design of spinal neuroprosthetic systems to improve standing and walking after neurological disorders.

Epidural electrical stimulation of posterior structures of the human lumbosacral cord: 2. quantitative analysis by computer modeling

Simulation of the computed recruitment order of an ensemble of ventral and dorsal root fibers shows a strong relation between electrode position and the order of muscle twitches which is based on the segmental arrangement of innervation of lower limb muscles.

Analysis of Models for External Stimulation of Axons

  • F. Rattay
  • Biology
    IEEE Transactions on Biomedical Engineering
  • 1986
The activating function is discussed for monopolar electrodes but the principle can be extended to arbitrary configurations of electrodes and the activity of the axon depends on the second space derivative of the extracellular medium.

Transcutaneous electrical spinal-cord stimulation in humans.

Can the human lumbar posterior columns be stimulated by transcutaneous spinal cord stimulation? A modeling study.

A detailed three-dimensional volume conductor model of the torso and the McIntyre-Richard-Grill axon model are used to calculate the thresholds of axons within the posterior columns in response to transcutaneous lumbar spinal cord stimulation.

Initiation and modulation of locomotor circuitry output with multisite transcutaneous electrical stimulation of the spinal cord in noninjured humans.

It is demonstrated that simultaneous stimulation at the cervical, thoracic, and lumbar levels induced coordinated stepping movements with a greater range of motion at multiple joints in five of six noninjured subjects.

Enabling Task‐Specific Volitional Motor Functions via Spinal Cord Neuromodulation in a Human With Paraplegia

Integration of sensory, spinal, and volitional descending inputs in regulation of human locomotion.

The hypothesis that spinal and plantar stimulation may be effective tools for enhancing the recovery of motor control in individuals with neurological injuries and disorders is supported.