Theoretical basis for genetic linkage analysis in autotetraploid species.

  title={Theoretical basis for genetic linkage analysis in autotetraploid species.},
  author={Zewei Luo and R. D. Zhang and Michael J. Kearsey},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={101 18},
Linkage analysis in autotetraploid species has been an historical challenge in quantitative genetics theory and is a stumbling block that urgently needs to be removed in the rapidly emerging genome research on this species, such as cultivated potato. This article presents theory of a full model of tetrasomic linkage and develops a statistical framework for the linkage analysis. The model considers both double reduction and recombination, the most essential features of tetrasomic inheritance… CONTINUE READING
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