Theoretical Basis for the Activity of Thalidomide

  title={Theoretical Basis for the Activity of Thalidomide},
  author={Christian Meierhofer and Stefan Dunzendorfer and Dr Christian J. Wiedermann},
The revival of thalidomide began shortly after the drug was withdrawn from the market because of its teratogenic properties. Therapeutic effects of thalidomide were found accidentally in leprosy patients with erythema nodosum leprosum (ENL). Subsequent research widened the understanding of the activity of thalidomide, and with improved methodology and the augmented background knowledge of immunology it was possible to interpret the properties of thalidomide more coherently. Effects on tumour… CONTINUE READING
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