Theophylline regulates inflammatory and neurotrophic factor signals in functional recovery after C2-hemisection in adult rats.

@article{Singh2012TheophyllineRI,
  title={Theophylline regulates inflammatory and neurotrophic factor signals in functional recovery after C2-hemisection in adult rats.},
  author={Lalit Pukhrambam Singh and Takhellambam Swornalata Devi and Kwaku D. Nantwi},
  journal={Experimental neurology},
  year={2012},
  volume={238 1},
  pages={79-88}
}
Recovery of respiratory activity in an upper cervical hemisection model (C2H) of spinal cord injury (SCI) can be induced by systemic theophylline administration 24-48 h after injury. The objectives in the present study are (1) to identify pro-inflammatory and neurotrophic factors expressed after C2H and (2) molecular signals involved in functional recovery… CONTINUE READING