Theophylline, fatigue, and diaphragm contractility: cellular levels of 45Ca and cAMP.

@article{Kolbeck1991TheophyllineFA,
  title={Theophylline, fatigue, and diaphragm contractility: cellular levels of 45Ca and cAMP.},
  author={Ralph C. Kolbeck and W. A. Speir},
  journal={Journal of applied physiology},
  year={1991},
  volume={70 5},
  pages={1933-7}
}
The relationship between variations in diaphragmatic contractility and corresponding changes in total tissue levels of 45Ca and adenosine 3',5'-cyclic monophosphate (cAMP) was examined. The contractile performance of perfused contracting rat diaphragms was manipulated with theophylline (10(-4) M), induced fatigue, or both. The increased contractility… CONTINUE READING