Theacrine, a special purine alkaloid with sedative and hypnotic properties from Cammelia assamica var. kucha in mice.

@article{Xu2007TheacrineAS,
  title={Theacrine, a special purine alkaloid with sedative and hypnotic properties from Cammelia assamica var. kucha in mice.},
  author={Jie-kun Xu and Hiroshi Kurihara and Liang Zhao and Xin-sheng Yao},
  journal={Journal of Asian natural products research},
  year={2007},
  volume={9 6-8},
  pages={
          665-72
        }
}
The central nervous system activities of theacrine (1,3,7,9-tetramethyluric acid), a purine alkaloid which is abundantly present in Camellia assamica var. kucha, were investigated in ambulatory activity, pentobarbital-induced sleep and forced swimming test in mice, compared with two other purine alkaloids, caffeine and theobromine. Caffeine treatment led to a marked increase in the ambulatory activity accompanied with decreasing of the immobility time in forced swimming test at both 10 and 30… CONTINUE READING
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