TheLac carrier protein inEscherichia coli

  title={TheLac carrier protein inEscherichia coli},
  author={H Ronald Kaback},
  journal={The Journal of Membrane Biology},
Although active transport (i.e., concentration of solute against a gradient at the expense of metabolic energy) has been a recognized phenomenon for many years, insight into the biochemistry of the reactions involved has begun to occur only recently. In the author's opinion, the reasons for the progression from the phenomenological to the molecular level are essentially threefold: (1) Formulation of the chemiosmotic hypothesis by Peter Mitchell (1961, 1963, 1966, 1968), which stipulates that… CONTINUE READING