The zinc chelator 1 , 10 - phenanthroline enhances the stimulatory effects of protein kinase C activators and staurosporine , but not sphingosine and H 202 , on phospholipase D activity in NIH 3 T 3 fibroblasts

Abstract

or inhibit, respectively, the stimulatory effects of PMA on PLD-mediated phospholipid hydrolysis. Instead, treatment of ['4C]cholineand [14C]ethanolamine-labelled NIH 3T3 fibroblasts with the high-affinity zinc chelator 1,10-phenanthroline (0.21 mM) for 20-30 min was found to enhance the stimulatory effects of PMA on PLD-mediated hydrolysis of… (More)

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@inproceedings{Kiss2005TheZC, title={The zinc chelator 1 , 10 - phenanthroline enhances the stimulatory effects of protein kinase C activators and staurosporine , but not sphingosine and H 202 , on phospholipase D activity in NIH 3 T 3 fibroblasts}, author={Zolt{\'a}n Kiss}, year={2005} }