The zebrafish embryo as a dynamic model of anoxia tolerance.

@article{Mendelsohn2008TheZE,
  title={The zebrafish embryo as a dynamic model of anoxia tolerance.},
  author={Bryce Abram Mendelsohn and Bethany L Kassebaum and Jonathan D. Gitlin},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2008},
  volume={237 7},
  pages={
          1780-8
        }
}
Developing organisms depend upon a delicate balance in the supply and demand of energy to adapt to variable oxygen availability, although the essential mechanisms determining such adaptation remain elusive. In this study, we examine reversible anoxic arrest and dynamic bioenergetic transitions during zebrafish development. Our data reveal that the duration of anoxic viability corresponds to the developmental stage and anaerobic metabolic rate. Diverse chemical inhibitors of mitochondrial… CONTINUE READING
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Proteomic analysis of anoxia tolerance in the developing zebrafish embryo.

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Coordination of development and metabolism in the pre-midblastula transition zebrafish embryo.

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