The yin and yang of tenascin-R in CNS development and pathology.

  title={The yin and yang of tenascin-R in CNS development and pathology.},
  author={Penka Pesheva and Rainer Probstmeier},
  journal={Progress in neurobiology},
  volume={61 5},
An important biological consequence of the initial interactions between the cell surface and its extracellular environment is the diversity of cellular responses ranging from overt repulsion or avoidance reaction to stable adhesion or final positioning. It is now evident that positive and negative guiding mechanisms are equally relevant to normal pattern formation during development and decisive for the outcome of a regenerative process. In this context, the present review summarizes the… CONTINUE READING

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