The yeast mitochondrial RNA polymerase specificity factor, MTF1, is similar to bacterial sigma factors.

@article{Jang1991TheYM,
  title={The yeast mitochondrial RNA polymerase specificity factor, MTF1, is similar to bacterial sigma factors.},
  author={Seh Hee Jang and Judith A. Jaehning},
  journal={The Journal of biological chemistry},
  year={1991},
  volume={266 33},
  pages={22671-7}
}
We have purified the protein that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. The N-terminal sequence of the 43-kDa specificity factor identified it as the product of the MTF1 gene described by Lisowsky and Michaelis (1988). We confirmed that MTF1 encoded the specificity factor by analyzing extracts from a yeast strain bearing a disruption of the gene. The extracts contained normal levels of core RNA polymerase but lacked selective… CONTINUE READING

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