The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases.

Abstract

We previously identified a complex of 3' --> 5' exoribonucleases, designated the exosome, that is expected to play a major role in diverse RNA processing and degradation pathways. Further biochemical and genetic analyses have revealed six novel components of the complex. Therefore, the complex contains 11 components, 10 of which are predicted to be 3' --> 5… (More)

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@article{Allmang1999TheYE, title={The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases.}, author={Christine Allmang and Elisabeth Petfalski and Alexandre V. Podtelejnikov and Matthias Mann and David Tollervey and Philip Mitchell}, journal={Genes & development}, year={1999}, volume={13 16}, pages={2148-58} }