The yeast Tsa1 peroxiredoxin is a ribosome-associated antioxidant.

@article{Trotter2008TheYT,
  title={The yeast Tsa1 peroxiredoxin is a ribosome-associated antioxidant.},
  author={Eleanor W. Trotter and Jonathan D. Rand and Jill Vickerstaff and Chris M Grant},
  journal={The Biochemical journal},
  year={2008},
  volume={412 1},
  pages={73-80}
}
The yeast Tsa1 peroxiredoxin, like other 2-Cys peroxiredoxins, has dual activities as a peroxidase and as a molecular chaperone. Its peroxidase function predominates in lower-molecular-mass forms, whereas a super-chaperone form predominates in high-molecular-mass complexes. Loss of TSA1 results in aggregation of ribosomal proteins, indicating that Tsa1… CONTINUE READING