The yeast PHO5 promoter: phosphate-control elements and sequences mediating mRNA start-site selection.

@article{Rudolph1987TheYP,
  title={The yeast PHO5 promoter: phosphate-control elements and sequences mediating mRNA start-site selection.},
  author={Hans Rudolph and A. Hinnen},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1987},
  volume={84 5},
  pages={1340-4}
}
Transcription of PHO5 is strongly regulated in response to the level of inorganic phosphate (Pi) present in the growth medium. We have identified elements required for PHO5 expression by analyzing small deletions in the PHO5 promoter on chromosome II. The results reveal three functionally different components of the PHO5 promoter: regulatory regions, a "TATA" element, and specific mRNA initiation sites. The regulatory regions contain related 19-base-pair (bp) dyad sequences acting as phosphate… CONTINUE READING