The yeast CPC2/ASC1 gene is regulated by the transcription factors Fhl1p and Ifh1p

@article{Kleinschmidt2005TheYC,
  title={The yeast CPC2/ASC1 gene is regulated by the transcription factors Fhl1p and Ifh1p},
  author={Malte Christian Kleinschmidt and Ramona Schulz and Gerhard H Braus},
  journal={Current Genetics},
  year={2005},
  volume={49},
  pages={218-228}
}
CPC2/ASC1 is one of the most abundantly transcribed genes in Saccharomyces cerevisiae. It encodes a ribosome-associated Gβ-like WD protein, which is highly conserved from yeast to man. Here, we show that CPC2 transcription depends on the carbon source and is induced during utilization of the sugar glucose. CPC2 promoter deletion and insertion analyses identified two upstream activation sequence elements for CPC2, which are required for basal expression and regulation. One of these upstream… CONTINUE READING