The wprA gene of Bacillus subtilis 168, expressed during exponential growth, encodes a cell-wall-associated protease.

@article{Margot1996TheWG,
  title={The wprA gene of Bacillus subtilis 168, expressed during exponential growth, encodes a cell-wall-associated protease.},
  author={Philippe Margot and Dimitri Karamata},
  journal={Microbiology},
  year={1996},
  volume={142 ( Pt 12)},
  pages={3437-44}
}
The nucleotide sequence of wprA, a protease-encoding gene of Bacillus subtilis 168, is reported. The gene, expressed during the exponential growth phase, belongs to a monocistronic operon. WprA is a 96 kDa polypeptide endowed with a signal peptide, as well as a propeptide. Upon processing and export, it gives rise to two previously identified cell-wall-bound proteins, CWBP23 and 52. Processing of WprA exhibits a novel feature of protein export, whereby removal of the middle part of the molecule… CONTINUE READING