The worldwide prevalence of multiple sclerosis

  title={The worldwide prevalence of multiple sclerosis},
  author={Maura Pugliatti and Stefano Sotgiu and Giulio Rosati},
  journal={Clinical Neurology and Neurosurgery},
Region with persistent high frequency of multiple sclerosis in Croatia and Slovenia
Are the Prevalence and Incidence of Multiple Sclerosis Changing?
The results suggest that this geographical region is currently a high-risk area for MS, since the incidence has increased markedly over the last 20 years, and demonstrates that prevalence and incidence of MS have been increasing in recent decades.
Prevalence of Multiple Sclerosis in the Republic of Moldova
This is the first report on sex- and age-specific prevalence of MS in the Republic of Moldova, which was lower than in Europe on average, but consistent with that of neighboring countries, Romania and Ukraine.
The prevalence of multiple sclerosis in central Italy
It is confirmed that MS occurs more frequently in central Italy than might be expected on the basis of the geographic-related distribution model, thus supporting the view that this is a high-risk area for the disease.
The epidemiology of multiple sclerosis in Latin America and the Caribbean: a systematic review
This study showed low frequency for MS in LAC compared with North American and European countries, and the role of environmental and genetic factors should be well studied, providing new insights about its etiology.
Prevalence of Multiple Sclerosis in Bogotá, Colombia
The prevalence estimates for Bogotá, confirm the city’s status as a low-risk area for MS.
Prevalence and Incidence of Multiple Sclerosis in Panama (2000–2005)
MS is in Panama a neurological pathology with a low prevalence and the results of this investigation improved early treatment and diagnosis of this disease.
Is it time to revise the classification of geographical distribution of multiple sclerosis?
Differences in the distribution of genetically susceptible populations, as determined by racial and ethnic backgrounds and differences in environmental risk are shown, supporting the reported geographic heterogeneity of MS prevalence.
Prevalence of Multiple Sclerosis in Isfahan, Iran
Isfahan could be considered as an area with a medium to high risk of MS in Isfahan, central part of Iran, in sharp contrast with the gradient hypothesis.
Multiple sclerosis in Latin America: A different disease course severity? A collaborative study from the MSBase Registry
The objective was to compare the course of MS between LA and other regions and found no difference in mean MSSS among patients from different regions, hemispheres or countries.


The prevalence of multiple sclerosis in the world: an update
Prevalence data imply that racial and ethnic differences are important in influencing the worldwide distribution of MS and that its geography must be interpreted in terms of the probable discontinuous distribution of genetic susceptibility alleles, which can however be modified by environment.
Descriptive epidemiology of multiple sclerosis in Europe in the 1980s: A critical overview
  • G. Rosati
  • Geography, Medicine
    Annals of neurology
  • 1994
The oversimplified but commonly accepted belief, based on the comparison of the prevalence studies conducted until 1980, that the distribution of multiple sclerosis (MS) in Europe is related to
Epidemiology of multiple sclerosis: a critical overview.
  • A. Sadovnick, G. Ebers
  • Medicine
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques
  • 1993
It is concluded that the epidemiology of MS cannot be explained by any single known environmental or genetic factor(s) in isolation and a combination of a heterogeneous distribution of both genetic and environmental factors appears to be required.
Multiple sclerosis Observations and reflections - a personal memoir
  • C. Poser
  • Medicine
    Journal of the Neurological Sciences
  • 1992
Validity of the epidemics of multiple sclerosis in the Faroe Islands.
It is concluded that PMSA is a single, widespread, specific, systemic infectious disease whose acquisition in virgin populations follows 2 years of exposure starting between age 11 and 45, which then produces CNMS in only a small proportion of the affected after a 6-year incubation period.
Analysis of the 'epidemic' of multiple sclerosis in the Faroe Islands. I. Clinical and epidemiological aspects.
The claim has been made that British troops introduced multiple sclerosis (MS), a transmissible disease, into the Faroe Islands during World War II, causing a three-tier epidemic which resulted in
Multiple sclerosis in the Faroe Islands: an epitome.
The Sardinian IDDM Study: 1. Epidemiology and geographical distribution of IDDM in Sardinia during 1989 to 1994
The finding of a small geographical variation within the island coupled with a marked temporal trend previously observed in data on military conscripts could be interpreted as evidence of a relatively recent environmental aetiological factor that was uniformly distributed across the island and had its effect in a genetically predisposed population.
Analysis of the 'epidemic' of multiple sclerosis in the Faroe Islands. II. Biostatistical aspects.
There was no epidemic of MS in the Faroe Islands because of the very small size of the sample, and the lack of concordance between the results of the various approaches leads to the conclusion that there was not an epidemic.
Prevalence and 4-year incidence of insulin-dependent diabetes mellitus in the province of Oristano (Sardinia, Italy)
The incidence and prevalence of type I diabetes mellitus are very high, ranking the province of Oristano among the highest in Europe.