The wide-domain carbon catabolite repressor CreA indirectly controls expression of the Aspergillus nidulans xlnB gene, encoding the acidic endo-beta-(1,4)-xylanase X(24).

@article{Orejas2001TheWC,
  title={The wide-domain carbon catabolite repressor CreA indirectly controls expression of the Aspergillus nidulans xlnB gene, encoding the acidic endo-beta-(1,4)-xylanase X(24).},
  author={Margarita Orejas and Andrew P Maccabe and JOS{\'E} A. P{\'E}REZ-GONZ{\'A}LEZ and Sanjay Kumar and Daniel Ram{\'o}n},
  journal={Journal of bacteriology},
  year={2001},
  volume={183 5},
  pages={1517-23}
}
The Aspergillus nidulans xlnB gene, which encodes the acidic endo-beta-(1,4)-xylanase X(24), is expressed when xylose is present as the sole carbon source and repressed in the presence of glucose. That the mutation creA(d)30 results in considerably elevated levels of xlnB mRNA indicates a role for the wide-domain repressor CreA in the repression of xlnB promoter (xlnBp) activity. Functional analyses of xlnBp::goxC reporter constructs show that none of the four CreA consensus target sites… CONTINUE READING