The vulnerable window for unidirectional block in cardiac tissue: characterization and dependence on membrane excitability and intercellular coupling.

@article{Shaw1995TheVW,
  title={The vulnerable window for unidirectional block in cardiac tissue: characterization and dependence on membrane excitability and intercellular coupling.},
  author={Robin Shaw and Yoram Rudy},
  journal={Journal of cardiovascular electrophysiology},
  year={1995},
  volume={6 2},
  pages={115-31}
}
INTRODUCTION Unidirectional block is a requisite event in the initiation of reentry in cardiac tissue, but its initiation and behavior in the presence of tissue pathologies remain poorly understood. Previous experimental and theoretical reports on vulnerability to unidirectional block under conditions of reduced cellular coupling and reduced membrane excitability have varied due to differences in experimental and simulation protocols. METHODS AND RESULTS We have addressed the issue of… CONTINUE READING

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