The von Restorff Effect in Amnesia: The Contribution of the Hippocampal System to Novelty-Related Memory Enhancements
@article{Kishiyama2004TheVR, title={The von Restorff Effect in Amnesia: The Contribution of the Hippocampal System to Novelty-Related Memory Enhancements}, author={Mark M. Kishiyama and Andrew P. Yonelinas and Michele M. Lazzara}, journal={Journal of Cognitive Neuroscience}, year={2004}, volume={16}, pages={15-23} }
The ability to detect novelty is a characteristic of all mammalian nervous systems (Sokolov, 1963), and it plays a critical role in memory in the sense that items that are novel, or distinctive, are remembered better than those that are less distinct (von Restorff, 1933). Although several brain areas are sensitive to stimulus novelty, it is not yet known which regions play a role in producing novelty-related effects on memory. In the current study, we investigated novelty effects on recognition…Â
60 Citations
A critical role of the human hippocampus in an electrophysiological measure of implicit memory
- Psychology, BiologyNeuroImage
- 2015
Novelty Enhancements in Memory Are Dependent on Lateral Prefrontal Cortex
- Psychology, BiologyThe Journal of Neuroscience
- 2009
Patients with lateral PFC damage were impaired in recollection- and familiarity-based recognition, and they did not exhibit a normal memory advantage for novel compared with non-novel items, providing neuropsychological evidence supporting a key role for the lateral P FC in producing stimulus novelty advantages in memory.
Any novelty in hippocampal formation and memory?
- Biology, PsychologyCurrent opinion in neurology
- 2005
Interindividual variability in the responsiveness of the hippocampal-novelty system may be genetically mediated, and personality factors can also play a role, which can have implications for interventions aimed at supporting memory and for the treatment of drug abuse.
The medial temporal lobe and recognition memory.
- Psychology, BiologyAnnual review of neuroscience
- 2007
Evidence from neuropsychological, neuroimaging, and neurophysiological studies of humans, monkeys, and rats indicates that different subregions of the MTL make distinct contributions to recollection and familiarity; the data suggest that the hippocampus is critical for recollection but not familiarity.
Which computational mechanisms operate in the hippocampus during novelty detection?
- Biology, PsychologyHippocampus
- 2007
It is concluded that a comparator mechanism may underlie the role of the hippocampus not only in detecting occurrences that are unexpected given specific associatively retrieved predictions, but also events that violate more abstract properties of the experimental context.
Anterior medial temporal lobe in human cognition: Memory for fear and the unexpected
- Biology, PsychologyCognitive neuropsychiatry
- 2006
Human functional magnetic resonance imaging experiments are presented that address the neurobiological processes underlying upregulation of memory for novel or emotional events and introduce a hypothesis that medial temporal connectivity with autonomic control centres may be central to this memory enhancement.
Bilateral Thalamic Lesions Affect Recollection-and Familiarity-Based Recognition Memory Judgments
- Psychology, BiologyCortex
- 2005
Novelty processing and memory impairment in Alzheimer's disease: A review
- Psychology, BiologyNeuroscience & Biobehavioral Reviews
- 2019
Electrophysiological analysis of the role of novelty in the von Restorff effect
- PsychologyBrain and behavior
- 2013
It was seen that cued recall was better for words presented in novel fonts than for words in a standard font (the von Restorff effect), and hypothesized that the N2–P3 complex would be more enhanced for novel words that were later recalled than for those not recalled.
Learning and Representation of Declarative Memories by Single Neurons in the Human Brain
- Biology, Psychology
- 2008
This work recorded single neurons and local field potentials in the human hippocampus, amygdala, and anterior cingulate cortex while subjects remembered, and later retrieved, the identity and location of pictures shown, to indicate whether plasticity was successful or not.
References
SHOWING 1-10 OF 53 REFERENCES
Episodic memory, amnesia, and the hippocampal–anterior thalamic axis
- Biology, PsychologyBehavioral and Brain Sciences
- 1999
By utilizing new information from both clinical and experimental studies with animals, the anatomy underlying anterograde amnesia has been reformulated and places critical importance on the efferents from the hippocampus via the fornix to the diencephalon.
Contribution of human hippocampal region to novelty detection
- Biology, PsychologyNature
- 1996
THE ability to respond to unexpected stimuli (the 'orienting response') is a fundamental characteristic of mammalian behaviour1, but the brain mechanisms by which novelty is detected remain poorly…
Analysis of a distributed neural system involved in spatial information, novelty, and memory processing
- Psychology, BiologyHuman brain mapping
- 2000
Investigation of regional dissociations in spatial information and novelty processing in the context of memory encoding using a 2 Ă— 2 factorial design provided evidence for a hierarchical independence in novelty processing characterized by increased dissociation from spatial information processing.
The von Restorff Effect in Visual Object Recognition Memory in Humans and Monkeys: The Role of Frontal/Perirhinal Interaction
- Psychology, BiologyJournal of Cognitive Neuroscience
- 1998
The results support an interaction between the perirhinal and frontal cortices in the processing of certain kinds of novel information that support visual object recognition memory.
The central role of the prefrontal cortex in directing attention to novel events.
- Psychology, BiologyBrain : a journal of neurology
- 2000
The physiological basis for the striking decrease of attention to novel events following frontal lobe injury is poorly understood. In this study, event-related potentials (ERPs) were recorded from…
Two functional components of the hippocampal memory system
- Psychology, BiologyBehavioral and Brain Sciences
- 1994
It is proposed that neocortical association areas maintain shortterm memories for specific items and events prior to hippocampal processing as well as providing the final repositories of long-term memory.
Three Cases of Enduring Memory Impairment after Bilateral Damage Limited to the Hippocampal Formation
- Psychology, BiologyThe Journal of Neuroscience
- 1996
The present results substantiate the idea that severity of memory impairment is dependent on locus and extent of damage within the hippocampal formation and that damage to the hippocampusal formation can cause temporally graded retrograde amnesia.
Bilateral Thalamic Lesions Affect Recollection-and Familiarity-Based Recognition Memory Judgments
- Psychology, BiologyCortex
- 2005
Effects of extensive temporal lobe damage or mild hypoxia on recollection and familiarity
- Psychology, BiologyNature Neuroscience
- 2002
It is found that the regions disrupted in mild hypoxia, such as the hippocampus, are centrally involved in conscious recollection, whereas the surrounding temporal lobe supports familiarity-based memory discrimination.
Prefrontal–Temporal Circuitry for Episodic Encoding and Subsequent Memory
- Psychology, BiologyThe Journal of Neuroscience
- 2000
The results suggest that regions that demonstrate a sensitivity to novelty may actively support encoding processes that impact subsequent explicit memory and multiple content-dependent prefrontal–temporal circuits support event encoding.