The voltage-sensitive sodium channel is a bell-shaped molecule with several cavities

  title={The voltage-sensitive sodium channel is a bell-shaped molecule with several cavities},
  author={C. Sato and Y. Ueno and K. Asai and K. Takahashi and M. Sato and A. Engel and Y. Fujiyoshi},
  • C. Sato, Y. Ueno, +4 authors Y. Fujiyoshi
  • Published 2001
  • Chemistry, Medicine
  • Nature
  • Voltage-sensitive membrane channels, the sodium channel, the potassium channel and the calcium channel operate together to amplify, transmit and generate electric pulses in higher forms of life. Sodium and calcium channels are involved in cell excitation, neuronal transmission, muscle contraction and many functions that relate directly to human diseases. Sodium channels—glycosylated proteins with a relative molecular mass of about 300,000 (ref. 5)—are responsible for signal transduction and… CONTINUE READING
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