The vitamin K-dependent carboxylase has been acquired by Leptospira pathogens and shows altered activity that suggests a role other than protein carboxylation.

@article{Rishavy2005TheVK,
  title={The vitamin K-dependent carboxylase has been acquired by Leptospira pathogens and shows altered activity that suggests a role other than protein carboxylation.},
  author={Mark A Rishavy and Kevin W Hallgren and Anna V Yakubenko and Richard L. Zuerner and Kurt W Runge and Kathleen L Berkner},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 41},
  pages={34870-7}
}
Leptospirosis is an emerging infectious disease whose pathology includes a hemorrhagic response, and sequencing of the Leptospira interrogans genome revealed an ortholog of the vitamin K-dependent (VKD) carboxylase as one of several hemostatic proteins present in the bacterium. Until now, the VKD carboxylase was known to be present only in the animal… CONTINUE READING