The vitamin E analogue α-TEA stimulates tumor autophagy and enhances antigen cross-presentation.

@article{Li2012TheVE,
  title={The vitamin E analogue α-TEA stimulates tumor autophagy and enhances antigen cross-presentation.},
  author={Y Li and Tobias Hahn and Kendra Garrison and Zhi-Hua Cui and Andrew P. Thorburn and Jacqueline Thorburn and Hong-ming Hu and Emmanuel T. Akporiaye},
  journal={Cancer research},
  year={2012},
  volume={72 14},
  pages={3535-45}
}
The semisynthetic vitamin E derivative alpha-tocopheryloxyacetic acid (α-TEA) induces tumor cell apoptosis and may offer a simple adjuvant supplement for cancer therapy if its mechanisms can be better understood. Here we report that α-TEA also triggers tumor cell autophagy and that it improves cross-presentation of tumor antigens to the immune system. α-TEA… CONTINUE READING