The vitamin D epidemic and its health consequences.

  title={The vitamin D epidemic and its health consequences.},
  author={Michael F Holick},
  journal={The Journal of nutrition},
  volume={135 11},
Vitamin D deficiency is now recognized as an epidemic in the United States. The major source of vitamin D for both children and adults is from sensible sun exposure. In the absence of sun exposure 1000 IU of cholecalciferol is required daily for both children and adults. Vitamin D deficiency causes poor mineralization of the collagen matrix in young children's bones leading to growth retardation and bone deformities known as rickets. In adults, vitamin D deficiency induces secondary… CONTINUE READING
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Vitamin D: the underappreciated D-lightful hormone that is important for skeletal and cellular health

  • MF Holick
  • Curr Opin Endocrinol Diabetes
  • 2002
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  • S. Khosla
  • 2001
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Vitamin D: from photosynthesis, metabolism, and action to clinical applications

  • R. Bouillon
  • DeGroot LJ, Jameson JL, editors. Endocrinology…
  • 2001
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The relation of solar radiation to cancer mortality in North America

  • FL Apperley
  • Cancer Res
  • 1941
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The calbindins: calbindin-D9K and calbindin-D28K

  • S Christakos, Y Liu, P Dhawan, X. Peng
  • Vitamin D. 2nd ed. London: Elsevier;
  • 2005
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