The visinin-like proteins VILIP-1 and VILIP-3 in Alzheimer's disease—old wine in new bottles

@inproceedings{Braunewell2012TheVP,
  title={The visinin-like proteins VILIP-1 and VILIP-3 in Alzheimer's disease—old wine in new bottles},
  author={Karl H. Braunewell},
  booktitle={Front. Mol. Neurosci.},
  year={2012}
}
The neuronal Ca(2+)-sensor (NCS) proteins VILIP-1 and VILIP-3 have been implicated in the etiology of Alzheimer's disease (AD). Genome-wide association studies (GWAS) show association of genetic variants of VILIP-1 (VSNL1) and VILIP-3 (HPCAL1) with AD+P (+psychosis) and late onset AD (LOAD), respectively. In AD brains the expression of VILIP-1 and VILIP-3 protein and mRNA is down-regulated in cortical and limbic areas. In the hippocampus, for instance, reduced VILIP-1 mRNA levels correlate with… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 152 references

Citation: Braunewell KH (2012) The visinin-like proteins VILIP-1 and VILIP3 in Alzheimer’s disease—old wine in new bottles

February
Front. Mol. Neurosci. 5:20. • 2012
View 9 Excerpts
Highly Influenced

Biomarkers of Alzheimer's disease

Neurobiology of Disease • 2009
View 7 Excerpts
Highly Influenced

Expression of the neuronal calcium sensor VILIP - 1 in the rat hippocam

K-H. Braunewell
Neuroscience • 2008
View 6 Excerpts
Highly Influenced

The calcium - myristoyl switch of neuronal calcium sensor ( NCS ) proteins : same biochemical principle but different calcium - dependent localization of VILIP - 3 and - 1 in hippocampal neurons

C. Spilker, K-H. Braunewell
Mol . Cell . Neurosci • 2003
View 8 Excerpts
Highly Influenced

Regulatory elements and functional implication for the formation of dimeric visinin-like protein-1.

Journal of peptide science : an official publication of the European Peptide Society • 2009
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…