The virophage as a unique parasite of the giant mimivirus

@article{Scola2008TheVA,
  title={The virophage as a unique parasite of the giant mimivirus},
  author={B. Scola and C. Desnues and I. Pagnier and C. Robert and L. Barrassi and G. Fournous and M. Merchat and M. Suzan-Monti and P. Forterre and E. Koonin and D. Raoult},
  journal={Nature},
  year={2008},
  volume={455},
  pages={100-104}
}
Viruses are obligate parasites of Eukarya, Archaea and Bacteria. Acanthamoeba polyphaga mimivirus (APMV) is the largest known virus; it grows only in amoeba and is visible under the optical microscope. Mimivirus possesses a 1,185-kilobase double-stranded linear chromosome whose coding capacity is greater than that of numerous bacteria and archaea. Here we describe an icosahedral small virus, Sputnik, 50 nm in size, found associated with a new strain of APMV. Sputnik cannot multiply in… Expand
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Mimivirus shows dramatic genome reduction after intraamoebal culture
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