The viral paradigm in type 1 diabetes: Who are the main suspects?

@article{RodriguezCalvo2016TheVP,
  title={The viral paradigm in type 1 diabetes: Who are the main suspects?},
  author={T. Rodriguez-Calvo and Somayeh Sabouri and F. Anquetil and M. V. von Herrath},
  journal={Autoimmunity reviews},
  year={2016},
  volume={15 10},
  pages={
          964-9
        }
}
Type 1 diabetes (T1D) is an autoimmune disease characterized by the loss of pancreatic beta cells in the islets of Langerhans. Although genetic predisposition plays an important role in T1D development, studies of identical twins suggest that environmental factors such as viruses and other pathogens may be critical triggers either through direct cytolytic effect and gradual beta cell destruction, or by bystander activation of the immune system. In addition, viruses may circumvent the host… Expand
42 Citations
Type 1 diabetes and viral infections: What is the relationship?
  • 17
Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes
  • 30
  • PDF
Intestinal virome changes precede autoimmunity in type I diabetes-susceptible children
  • 116
  • PDF
The "Three Amigos" lurking behind type 1 diabetes: Hygiene, gut microbiota and viruses.
  • 7
  • PDF
Type 1 Diabetes: Interferons and the Aftermath of Pancreatic Beta-Cell Enteroviral Infection
  • 1
  • PDF
The Challenges of Identifying Environmental Determinants of Type 1 Diabetes: In Search of the Holy Grail
  • 1
  • PDF
Study of 2009 H1N1 Pandemic Influenza Virus as a Possible Causative Agent of Diabetes
  • 9
  • PDF
Rotavirus and Type 1 Diabetes-is there a connection? A synthesis of the evidence.
  • 2
  • PDF
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 78 REFERENCES
Protection against or triggering of Type 1 diabetes? Different roles for viral infections
  • 42
The role of viruses in human diabetes
  • 280
  • PDF
Fulminant type 1 diabetes—an important subtype in East Asia
  • 71
Next-generation sequencing for viruses in children with rapid-onset type 1 diabetes
  • 29
  • PDF
Viral Infection of Engrafted Human Islets Leads to Diabetes
  • 35
  • PDF
...
1
2
3
4
5
...