The vasopressin system--from antidiuresis to psychopathology.

  title={The vasopressin system--from antidiuresis to psychopathology.},
  author={Elisabeth Frank and Rainer Landgraf},
  journal={European journal of pharmacology},
  volume={583 2-3},
Vasopressin is a neuropeptide with multiple functions. In addition to its predominantly antidiuretic action after peripheral secretion from the posterior pituitary, it seems to fulfill--together with its receptor subtype--all requirements for a neuropeptide system critically involved in higher brain functions, including cognitive abilities and emotionality. Following somatodendritic and axonal release in distinct brain areas, vasopressin acts as a neuromodulator and neurotransmitter in multiple… CONTINUE READING