The varicella-zoster virus genome.

@article{Cohen2010TheVV,
  title={The varicella-zoster virus genome.},
  author={Jeffrey I. Cohen},
  journal={Current topics in microbiology and immunology},
  year={2010},
  volume={342},
  pages={
          1-14
        }
}
The varicella-zoster virus (VZV) genome contains at least 70 genes, and all but six have homologs in herpes simplex virus (HSV). Cosmids and BACs corresponding to the VZV parental Oka and vaccine Oka viruses have been used to "knockout" 34 VZV genes. Seven VZV genes (ORF4, 5, 9, 21, 29, 62, and 68) have been shown to be required for growth in vitro. Recombinant viruses expressing several markers (e.g., beta-galactosidase, green fluorescence protein, luciferase) and several foreign viral genes… CONTINUE READING

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