The varicella-zoster virus (VZV) open-reading frame 29 protein acts as a modulator of a late VZV gene promoter.

@article{Boucaud1998TheVV,
  title={The varicella-zoster virus (VZV) open-reading frame 29 protein acts as a modulator of a late VZV gene promoter.},
  author={Dwayne Boucaud and Hiroshi Yoshitake and John Hay and William T. Ruyechan},
  journal={The Journal of infectious diseases},
  year={1998},
  volume={178 Suppl 1},
  pages={S34-8}
}
Transient expression assays have shown that the varicella-zoster virus (VZV) open-reading frame (ORF) 29 gene product can act as a modulator of VZV gene expression. The ORF 29 protein alone does not appear to have any effect on transcription; however, in its presence, changes in the level of reporter gene activity mediated by the VZV immediate early (IE) 62 major transactivator are seen. Increased expression was observed in human fibroblasts, MeWo cells, HeLa cells, and T cells. In contrast… CONTINUE READING