The value of machine perfusion biomarker concentration in DCD kidney transplantations.

@article{Hoogland2013TheVO,
  title={The value of machine perfusion biomarker concentration in DCD kidney transplantations.},
  author={E. R. Pieter Hoogland and Eva E de Vries and Maarten H. L. Christiaans and Bjorn Winkens and Maarten G. J. Snoeijs and L. W. Ernest van Heurn},
  journal={Transplantation},
  year={2013},
  volume={95 4},
  pages={603-10}
}
BACKGROUND Donation after cardiac death (DCD) increases the number of donor kidneys but is associated with more primary nonfunction (PNF) and delayed graft function (DGF). It has been suggested that biomarkers in the preservation solution of machine perfused kidneys may predict PNF, although evidence is lacking. METHODS We analyzed the diagnostic accuracy of the perfusate biomarkers glutathione S-transferase, lactate dehydrogenase (LDH), heart-type fatty acid binding protein, redox-active… CONTINUE READING