The validity of the Aspergillus nidulans linkage map.

  title={The validity of the Aspergillus nidulans linkage map.},
  author={A. John Clutterbuck},
  journal={Fungal genetics and biology : FG & B},
  volume={21 3},
The Aspergillus nidulans linkage map is reviewed as a background to physical mapping by cosmid cross-hybridization and genome sequencing. DNA-based methods depend on contiguity, so that the resulting maps are only as good as the weakest link, whereas each new marker added to a linkage map can provide independent confirmation of the positions of its neighbors. For all eight chromosomes of A. nidulans a reliable framework has been provided by analysis of mitotic crossing over, in many cases… CONTINUE READING

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