The vagina as a route for drug delivery: a review
@article{Srikrishna2012TheVA, title={The vagina as a route for drug delivery: a review}, author={S. Srikrishna and L. Cardozo}, journal={International Urogynecology Journal}, year={2012}, volume={24}, pages={537-543} }
Overactive bladder (OAB) syndrome has a significant deleterious impact on quality of life. After conservative therapy and bladder retaining, antimuscarinic drugs remain the mainstay of OAB management. Oral therapy is associated with frequent side effects, leading to the development of alternative agents and formulations or the use of novel routes of drug administration, such as the vaginal route. The vagina is often ideal for drug delivery because it allows the use of lower doses, maintains… Expand
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References
SHOWING 1-10 OF 63 REFERENCES
Drug delivery by the intravaginal route.
- Medicine
- Critical reviews in therapeutic drug carrier systems
- 2000
- 118
Development of a Mucoadhesive Dosage Form for Vaginal Administration
- Chemistry, Medicine
- Drug development and industrial pharmacy
- 2001
- 70
Vaginal ring delivery of hormone replacement therapy – a review
- Medicine
- Expert opinion on pharmacotherapy
- 2003
- 42
Microdose intravaginal levonorgestrel contraception: a multicentre clinical trial. I. Contraceptive efficacy and side effects. World Health Organization. Task Force on Long-Acting Systemic Agents for Fertility Regulation.
- Medicine
- Contraception
- 1990
- 76
Absorption Kinetics of Misoprostol With Oral or Vaginal Administration
- Medicine
- Obstetrics and gynecology
- 1997
- 630
Novel vaginal danazol ring therapy for pelvic endometriosis, in particular deeply infiltrating endometriosis.
- Medicine
- Human reproduction
- 1998
- 67
- PDF
Propranolol concentrations in plasma after insertion into the vagina.
- Medicine
- British medical journal
- 1983
- 41
- PDF
Vaginal Bromocriptine: Pharmacology and Effect on Serum Prolactin in Normal Women
- Medicine
- Obstetrics and gynecology
- 1988
- 49