The vagal nerve as a link between the nervous and immune system in the instance of polymicrobial sepsis

@article{Kessler2006TheVN,
  title={The vagal nerve as a link between the nervous and immune system in the instance of polymicrobial sepsis},
  author={Wolfram Kessler and Tobias Traeger and Alexandra Westerholt and Friederike Neher and Marlene Mikulcak and Antje R. M{\"u}ller and Stefan Heinrich Maier and C. -D. Heidecke},
  journal={Langenbeck's Archives of Surgery},
  year={2006},
  volume={391},
  pages={83-87}
}
The role of the vagal nerve in the autonomic nervous system is widely well known. Recently, an additional function was revealed serving as a connector between the nervous and immune system. This connection is called the “cholinergic inflammatory pathway.” Through stimulation of the acetylcholine receptors located upon the macrophages, the “unspecific” immune system can be directly influenced. The vagal nerve was completely transected directly posterior to its passage through the diaphragm. The… CONTINUE READING

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