The vaccine efficacy of native paramyosin (Sj-97) against Chinese Schistosoma japonicum.

One of the promising anti-schistosome vaccine candidates currently under investigation is paramyosin, a 97-kDa myofibrillar protein located in the muscles and tegument of schistosome worms. Here we describe the results of two vaccination/challenge experiments undertaken in mice using native paramyosin isolated from adult worms of a Chinese strain of… CONTINUE READING