The utility of the general practice research database to examine selected congenital heart defects: a validation study.

@article{Wurst2007TheUO,
  title={The utility of the general practice research database to examine selected congenital heart defects: a validation study.},
  author={Keele E. Wurst and Sara A. Ephross and James P Loehr and Douglas W. Clark and Harry A. Guess},
  journal={Pharmacoepidemiology and drug safety},
  year={2007},
  volume={16 8},
  pages={867-77}
}
OBJECTIVE The purpose of this research was (1) to validate that ventricular septal defect (VSD), tetralogy of Fallot (TOF), and coarctation of the aorta (COA) can be studied in the UK General practice research database (GPRD) and (2) to understand which of the available GPRD components (computerized medical records, questionnaires, and maternal/infant free text) provide maximal information about these heart defects. METHODS Using a practitioner questionnaire, the positive predictive value… CONTINUE READING

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