The utility of poly(γ-glutamic acid) nanoparticles as antigen delivery carriers in dendritic cell-based cancer immunotherapy.

Abstract

Cytotoxic T-lymphocytes (CTLs) specific for tumor-associated antigens (TAAs) act in the immune surveillance system as major effector cells to eliminate malignant cells. Immunization with TAA-loaded dendritic cells (DCs) has great potential for treating cancer, because DCs are potent antigen-presenting cells capable of inducing antigen-specific CTLs by the… (More)

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Cite this paper

@article{Matsuo2010TheUO, title={The utility of poly(γ-glutamic acid) nanoparticles as antigen delivery carriers in dendritic cell-based cancer immunotherapy.}, author={Keisuke Matsuo and Yumiko Ishii and Kazuhiko Matsuo and Tomoyo Yoshinaga and Mitsuru Akashi and Yohei Mukai and Yasuo Yoshioka and Naoki Okada and Shinsaku Nakagawa}, journal={Biological & pharmaceutical bulletin}, year={2010}, volume={33 12}, pages={2003-7} }