The utility of clinical predictors of acute lung injury: towards prevention and earlier recognition.

@article{Levitt2010TheUO,
  title={The utility of clinical predictors of acute lung injury: towards prevention and earlier recognition.},
  author={Joseph E Levitt and Michael A. Matthay},
  journal={Expert review of respiratory medicine},
  year={2010},
  volume={4 6},
  pages={785-97}
}
Despite significant advances in our understanding of the pathophysiology of acute lung injury, a lung-protective strategy of mechanical ventilation remains the only therapy with a proven survival advantage. Numerous pharmacologic therapies have failed to show benefit in multicenter clinical trials. The paradigm of early, goal-directed therapy of sepsis suggests greater clinical benefit may derive from initiating therapy prior to the onset of respiratory failure that requires mechanical… CONTINUE READING
7 Citations
95 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 95 references

Similar Papers

Loading similar papers…