The uterine environment modulates trophectodermal POU5F1 levels in equine blastocysts.

@article{Choi2009TheUE,
  title={The uterine environment modulates trophectodermal POU5F1 levels in equine blastocysts.},
  author={Young Ho Choi and H D Harding and David L. Hartman and A D Obermiller and Satoshi Kurosaka and K J Mclaughlin and Katrin Hinrichs},
  journal={Reproduction},
  year={2009},
  volume={138 3},
  pages={
          589-99
        }
}
The reported patterns of trophectodermal expression of POU5F1 protein in blastocysts vary among species, and are possibly related to the differences in placental growth and function. This study investigated the pattern of embryonic POU5F1 expression in the horse, a species with delayed placental formation. Immature equine oocytes expressed POU5F1 protein in the cytoplasm and nucleus. Staining for POU5F1 protein in in vitro-produced (IVP) embryos decreased to day 5 of culture, then the nuclear… CONTINUE READING

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