The usefulness of determining des-gamma-carboxy prothrombin by sensitive enzyme immunoassay in the early diagnosis of patients with hepatocellular carcinoma.

@article{Mita1998TheUO,
  title={The usefulness of determining des-gamma-carboxy prothrombin by sensitive enzyme immunoassay in the early diagnosis of patients with hepatocellular carcinoma.},
  author={Yoshinori Mita and Yutaka Aoyagi and Masahiko Yanagi and Takeshi Suda and Yoshihiko Suzuki and Hitoshi Asakura},
  journal={Cancer},
  year={1998},
  volume={82 9},
  pages={1643-8}
}
BACKGROUND Measurements of serum concentrations of des-gamma-carboxy prothrombin (DCP) are widely used for diagnosing hepatocellular carcinoma (HCC). However, the DCP is not always sensitive enough to detect small HCCs. In the current study, the authors investigated the usefulness of DCP in the early diagnosis of HCC, using a more sensitive enzyme immunoassay than is conventionally employed. METHODS The authors examined 148 serum samples with DCP concentrations from a conventional assay of… CONTINUE READING
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