The use of whole-body retention of Tc-99m diphosphonate in the diagnosis of metabolic bone disease.

@article{Fogelman1978TheUO,
  title={The use of whole-body retention of Tc-99m diphosphonate in the diagnosis of metabolic bone disease.},
  author={Ignac Fogelman and Rodney G. Bessent and John Robert Turner and Dennis L. Citrin and Iain T. Boyle and William R. Greig},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  year={1978},
  volume={19 3},
  pages={270-5}
}
The limited role of bone scanning in the diagnosis of metabolic bone disease might be considerably improved by accurate quantification of skeletal uptake of the radiopharmaceutical. Using a standard shadow-shield whole-body monitor, we have measured whole-body retention (WBR) of Tc-99m HEDP up to 24 hr in 11 patients with renal osteodystrophy (mean WBR 88.6% at 24 hr); in ten patients with Paget's disease (mean 56.9%); in seven patients with osteomalacia (mean 40.7%); in five patients with… CONTINUE READING

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