The use of whole blood in a dipstick assay for detection of antibodies to Mycobacterium leprae: a field evaluation.

@article{BhrerSkula1998TheUO,
  title={The use of whole blood in a dipstick assay for detection of antibodies to Mycobacterium leprae: a field evaluation.},
  author={Samira B{\"u}hrer-S{\'e}kula and Maristela G Cunha and Wanderley Almeida Ferreira and Paul R. Klatser},
  journal={FEMS immunology and medical microbiology},
  year={1998},
  volume={21 3},
  pages={197-201}
}
We describe a further simplification of a dipstick assay for the detection of antibodies to phenolic glycolipid I of Mycobacterium leprae by using whole blood and evaluated the assay performance in the leprosy endemic area of Amazonas in Brazil. The agreement with the 'gold' standard ELISA was 94.9% (kappa value = 0.87). This simple assay may be useful to identify those at risk of developing leprosy, for example among contacts of leprosy patients at lower levels in the health services. 

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