• Corpus ID: 20311081

The use of vitamin B1 as a perineural adjuvant to middle interscalene block for postoperative analgesia after shoulder surgery.

  title={The use of vitamin B1 as a perineural adjuvant to middle interscalene block for postoperative analgesia after shoulder surgery.},
  author={Fernando Alemanno and Daniela Ghisi and Brigitte Westermann and Anela Bettoni and Andrea Fanelli and Luca La Colla and Giorgio Francesco Danelli and Bruno M Cesana},
  journal={Acta bio-medica : Atenei Parmensis},
  volume={87 1},
BACKGROUND Perineural administration of thiamine, via axonal flow, could strenghthen synthesis of ACh in the dorsal horn inhibitory interneurons, thus potentiating analgesia. The purpose of the present retrospective analysis is therefore to investigate whether adding perineurally 2 mg/Kg of thiamine to 0.75% levobupivacaine in patients undergoing middle interscalene block may prolong the duration of analgesia. METHOD The hospital records of all ASA status 1-2 patients, undergoing a single… 

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