The use of tranexamic acid to reduce blood loss during total knee arthroplasty.

@article{Hynes2003TheUO,
  title={The use of tranexamic acid to reduce blood loss during total knee arthroplasty.},
  author={Matthew C Hynes and Peter R Calder and Gareth Scott},
  journal={The Knee},
  year={2003},
  volume={10 4},
  pages={375-7}
}
HYPOTHESIS The fall in haemoglobin following unilateral total knee arthroplasty is reduced by tranexamic acid administration. METHODS 60 patients were studied in total, 30 received tranexamic acid 10 mg/kg on induction and a further dose shortly before the release of the tourniquet. Surgery was performed by the senior author in a standardised fashion using the Freeman Samuelson cemented total knee replacement. Haemoglobin levels were measured 2 weeks pre and 3 days post operatively. Any… CONTINUE READING

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