The use of the single radial haemolysis test for assessing antibody response and protective antibody levels in an influenza B vaccine study.

@article{Goodeve1983TheUO,
  title={The use of the single radial haemolysis test for assessing antibody response and protective antibody levels in an influenza B vaccine study.},
  author={Anne C Goodeve and Roy Jennings and Chris W Potter},
  journal={Journal of biological standardization},
  year={1983},
  volume={11 4},
  pages={289-96}
}
Single radial haemolysis (SRH) and HAI tests were used to determine the levels of antibody in sera obtained from 118 volunteers taking part in a study of influenza B/Hong Kong/73 subunit vaccine. The two tests gave similar overall results, and showed good correlation, but SRH appeared to be more sensitive for the detection of low concentrations of antibody. A greater than or equal to 45% increase in SRH zone area was found to be equivalent to a significant increase in antibody titre and on the… CONTINUE READING

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