The use of the mouse peritoneal cavity for screening for biocompatibility of polymers.


The mouse peritoneal cavity was evaluated as a possible model for the preliminary screening of polymeric implant materials. The phagocytic cells of the cavity were stimulated prior to implant insertion by intraperitoneal injection of thioglycollate, glycogen, or sodium caseinate. Small, cylindrical polymeric implants of polyethylene… (More)


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